Fig. 2. Effects of VEGF-A164 antibody (ab, 1, 5 μg) injected intracisternally on CFA-induced thermal hyperalgesia. Neither intracisternal administration of 1 μg VEGF-A164 antibody nor vehicle affected head withdrawal latency time in CFA-treated rats. However, intracisternal administration of 5 μg VEGF-A164 antibody significantly increased head withdrawal latency time in CFA-treated rats. There were six animals in each group. *p<0 .05, VEGF-A164 antibody- vs. vehicle-treated group.
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