Oral Biol Res 2019; 43(2): 155-160  https://doi.org/10.21851/obr.43.02.201906.155
Alveolar ridge preservation following extraction of multiple anterior teeth with and without adjunctive enamel matrix derivative: A case report
Bo-Ram Nam1 ,2†, Yeon-Tae Kim1 ,2†, Seong-Nyum Jeong1 ,2, Jae-Hong Lee1 ,2*
1Department of Periodontology, Wonkwang University Daejeon Dental Hospital, Wonkwang University College of Dentistry, Daejeon, Korea 
2Institute of Wonkwang Dental Research, Wonkwang University College of Dentistry, Iksan, Korea
Correspondence to: Jae-Hong Lee, Department of Periodontology, Wonkwang University Daejeon Dental Hospital, Wonkwang University College of Dentistry, 77 Dunsan-ro, Seo-gu, Daejeon 35233, Korea. Tel: +82-42-366-1114, Fax: +82-42-366-1115, E-mail: ljaehong@gmail.com

These authors contributed equally to this work.
Received: April 8, 2019; Revised: April 27, 2019; Accepted: May 7, 2019; Published online: June 30, 2019.
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This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
The objective of this study was to evaluate the dynamics of bone dimensional change in extraction sockets with alveolar ridge preservation (ARP) procedure with or without enamel matrix derivatives (EMD). ARP was performed in two patients after extraction of maxillary central incisors and lateral incisors. Deproteinized bovine bone mineral with 10% collagen covered by two layers of a native bilayer collagen membrane with adjunctive use of EMD (patient 1) and without EMD (patient 2). Radiological and clinical findings: adjunctive use of EMD in ARP showed similar horizontal and vertical bone dimensional changes and soft tissue healing outcomes (spontaneous bleeding, persistent swelling, and ulceration) but the duration of postoperative pain and swelling was reduced.
Keywords: Bone regeneration, Enamel matrix derivatives, Wound healing


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