Oral Biol Res 2019; 43(1): 110-114  https://doi.org/10.21851/obr.43.01.201903.110
Dental implant restoration of mandibular bone necrosis defects caused by use of paraformaldehyde-containing paste: A case report
Won-Pyo Lee1 , Ho-Keel Hwang2 , Hyoung-Hoon Jo2*
1Department of Periodontology, School of Dentistry, Chosun University, Gwangju, Korea
2Department of Conservative Dentistry, School of Dentistry, Chosun University, Gwangju, Korea
Correspondence to: Hyoung-Hoon Jo, Department of Conservative Dentistry, School of Dentistry, Chosun University, 309 Pilmun-daero, Dong-gu, Gwangju 61452, Korea. Tel: +82-62-220-3840, Fax: +82-62-223-9064, E-mail: joyendo@hanmail.net
Received: October 30, 2018; Revised: December 8, 2018; Accepted: December 11, 2018; Published online: March 31, 2019.
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This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Depulpin, is mainly composed of paraformaldehyde, and was widely been used in the past for root canal treatment due to its ease of use. However, its use was prohibited in Korea after several side effects of paraformaldehyde on periodontal tissue were reported. This case report demonstrates a successful dental implant restoration using platelet rich fibrin and recombinant human bone morphogenetic protein-2 for an acute mandibular bone necrosis caused by use of paraformaldehyde-containing paste.
Keywords: Dental implants, Depulpin, Osteomyelitis, Osteonecrosis, Paraformaldehyde

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